Tabel Aminoacizi [PDF]

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Zitiervorschau

α –Aminoacizi din proteine

Aminoacid

Simbol

Structura

pK1 (COOH)

pK2 (NH2)

2.4

9.8

2.4

9.9

2.2

9.7

2.3

9.7

2.3

9.8

2.2

9.2

≈13

2.1

9.1

≈13

1.9

10.8

8.3

2.1

9.3

pKR

Aminoacizi cu radicali alifatici

Glicina

Alanina*

CH2

Gly–G

+ NH

CH3

Ala–A

Val–V

Leucina*

Izoleucina*

Leu–L

Ile–I

CH3

CH3

_

CH

COO 3

_

CH CH

CH3 CH3

COO

+ NH

CH CH2

3

CH +

CH2

_

3

+ NH

CH3 Valina*

COO

CH

COO

_

NH3 CH

_

COO

+

CH3 NH3 Aminoacizi cu grupe hidroxil

Serina

Treonina*

Ser–S

Thr–T

HO

CH2

_

CH COO +

NH3

H 3C

_

CH CH COO +

OH NH3 Aminoacizi cu sulf

Cisteina

Metionina*

Cys–C

Met–M

HS

CH2

_

CH COO +

NH3

CH3

S

(CH2)2

_

CH COO

+

NH3

Aminoacizi acizi şi derivaţi _ Acid aspartic

Asparagina

OOC CH2

Asp–D

+ NH

H2N

Asn–N

C CH2

Glutamina

Glu–E

Gln–Q

COO

+ NH

O

OOC CH2 CH2

C

2.1

8.8

2.1

9.5

2.2

9.1

1.8

9.0

12.5

2.2

9.2

10.8

1.8

9.2

6.0

2.2

9.2

2.2

9.1

_

COO

4.1

3

_

CH + NH

O

3.9

3

CH

CH2 CH2

9.9

_

COO

+ NH

H2N

2.0

3

CH

_ Acid glutamic

_

CH

COO 3

Aminoacizi bazici

HN Arginina

Arg–R

CH2

+

CH2 CH2

C NH2

CH

_

COO

+

NH3

NH2 +

Lizina

H3N

Lys–K

(CH2)4

+

NH3

CH2 Histidina*

_

CH COO

His–H

HN

_

CH COO +

NH3

+

NH

Aminoacizi cu nuclee aromatice

Fenilalanina*

CH2

Phe–F

_

CH COO +

NH3

Tirozina

Tyr–Y

HO

CH2

_

CH COO +

NH3

10.1

CH2 Triptofan*

CH COO +

NH3

Trp–W

_

2.4

9.4

2.0

10.6

N H Imino-acizi

Prolina

_

+

Pro–P

COO

N H

H